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Targeting peptidyl-prolyl isomerase 1 in experimental pulmonary arterial hypertension

BACKGROUND: Pulmonary arterial hypertension (PAH) is a progressive disease characterised by pro-proliferative and anti-apoptotic phenotype in vascular cells, leading to pulmonary vascular remodelling and right heart failure. Peptidyl-prolyl cis/trans isomerase, NIMA interacting 1 (Pin1), a highly co...

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Detalles Bibliográficos
Autores principales: Rai, Nabham, Sydykov, Akylbek, Kojonazarov, Baktybek, Wilhelm, Jochen, Manaud, Grégoire, Veeroju, Swathi, Ruppert, Clemens, Perros, Frédéric, Ghofrani, Hossein Ardeschir, Weissmann, Norbert, Seeger, Werner, Schermuly, Ralph T., Novoyatleva, Tatyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403440/
https://www.ncbi.nlm.nih.gov/pubmed/35058248
http://dx.doi.org/10.1183/13993003.01698-2021