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Scutellarin Protects Against Mitochondrial Reactive Oxygen Species-Dependent NLRP3 Inflammasome Activation to Attenuate Intervertebral Disc Degeneration

Intervertebral disc degeneration (IVDD) is a predominant cause of disc herniation and is widespread worldwide. Inflammatory responses, mitochondrial dysfunction, and extracellular matrix degradation are known to be involved in IVDD. Scutellarin, an active ingredient extracted from Erigeron breviscap...

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Detalles Bibliográficos
Autores principales: Wang, Zihao, Zhang, Pengfei, Zhao, Yunpeng, Yu, Feiran, Wang, Shaoyi, Liu, Kaiwen, Cheng, Xiang, Shi, Jie, He, Qiting, Xia, Yanni, Cheng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403485/
https://www.ncbi.nlm.nih.gov/pubmed/36032701
http://dx.doi.org/10.3389/fbioe.2022.883118