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Scutellarin Protects Against Mitochondrial Reactive Oxygen Species-Dependent NLRP3 Inflammasome Activation to Attenuate Intervertebral Disc Degeneration
Intervertebral disc degeneration (IVDD) is a predominant cause of disc herniation and is widespread worldwide. Inflammatory responses, mitochondrial dysfunction, and extracellular matrix degradation are known to be involved in IVDD. Scutellarin, an active ingredient extracted from Erigeron breviscap...
Autores principales: | Wang, Zihao, Zhang, Pengfei, Zhao, Yunpeng, Yu, Feiran, Wang, Shaoyi, Liu, Kaiwen, Cheng, Xiang, Shi, Jie, He, Qiting, Xia, Yanni, Cheng, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403485/ https://www.ncbi.nlm.nih.gov/pubmed/36032701 http://dx.doi.org/10.3389/fbioe.2022.883118 |
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