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CaMKII T286 phosphorylation has distinct essential functions in three forms of long-term plasticity

The Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) mediates long-term potentiation or depression (LTP or LTD) after distinct stimuli of hippocampal NMDA-type glutamate receptors (NMDARs). NMDAR-dependent LTD prevails in juvenile mice, but a mechanistically different form of LTD can be readil...

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Detalles Bibliográficos
Autores principales: Cook, Sarah G., Rumian, Nicole L., Bayer, K. Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403491/
https://www.ncbi.nlm.nih.gov/pubmed/35872016
http://dx.doi.org/10.1016/j.jbc.2022.102299