Cargando…

SUMOylation of microtubule-cleaving enzyme KATNA1 promotes microtubule severing and neurite outgrowth

Katanin p60 ATPase-containing subunit A1 (KATNA1) is a microtubule-cleaving enzyme that regulates the development of neural protrusions through cytoskeletal rearrangements. However, the mechanism underlying the linkage of the small ubiquitin-like modifier (SUMO) protein to KATNA1 and how this modifi...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Shaojin, Liang, Yaozhong, Zou, Jianyu, Cai, Zhenbin, Yang, Hua, Yang, Jie, Zhang, Yunlong, Lin, Hongsheng, Zhang, Guowei, Tan, Minghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403493/
https://www.ncbi.nlm.nih.gov/pubmed/35868557
http://dx.doi.org/10.1016/j.jbc.2022.102292