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SUMOylation of microtubule-cleaving enzyme KATNA1 promotes microtubule severing and neurite outgrowth
Katanin p60 ATPase-containing subunit A1 (KATNA1) is a microtubule-cleaving enzyme that regulates the development of neural protrusions through cytoskeletal rearrangements. However, the mechanism underlying the linkage of the small ubiquitin-like modifier (SUMO) protein to KATNA1 and how this modifi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403493/ https://www.ncbi.nlm.nih.gov/pubmed/35868557 http://dx.doi.org/10.1016/j.jbc.2022.102292 |