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Molecular clones of genetically distinct hepatitis B virus genotypes reveal distinct host and drug treatment responses

BACKGROUND & AIMS: HBV exhibits wide genetic diversity with at least 9 genotypes (GTs), which differ in terms of prevalence, geographic distribution, natural history, disease progression, and treatment outcome. However, differences in HBV replicative capacity, gene expression, and infective capa...

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Detalles Bibliográficos
Autores principales: Liu, Yongzhen, Park, Debby, Cafiero, Thomas R., Bram, Yaron, Chandar, Vasuretha, Tseng, Anna, Gertje, Hans P., Crossland, Nicholas A., Su, Lishan, Schwartz, Robert E., Ploss, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403497/
https://www.ncbi.nlm.nih.gov/pubmed/36035359
http://dx.doi.org/10.1016/j.jhepr.2022.100535