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Molecular clones of genetically distinct hepatitis B virus genotypes reveal distinct host and drug treatment responses
BACKGROUND & AIMS: HBV exhibits wide genetic diversity with at least 9 genotypes (GTs), which differ in terms of prevalence, geographic distribution, natural history, disease progression, and treatment outcome. However, differences in HBV replicative capacity, gene expression, and infective capa...
Autores principales: | Liu, Yongzhen, Park, Debby, Cafiero, Thomas R., Bram, Yaron, Chandar, Vasuretha, Tseng, Anna, Gertje, Hans P., Crossland, Nicholas A., Su, Lishan, Schwartz, Robert E., Ploss, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403497/ https://www.ncbi.nlm.nih.gov/pubmed/36035359 http://dx.doi.org/10.1016/j.jhepr.2022.100535 |
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