Posaconazole inhibits the stemness of cancer stem-like cells by inducing autophagy and suppressing the Wnt/β-catenin/survivin signaling pathway in glioblastoma

Posaconazole (POS) has been reported to present potential antitumor activity for glioblastoma (GBM). However, its molecular mechanisms remain unclear. In this study, we found that POS has potent cytotoxicity and inhibits cell viability and proliferation in GBM. In addition, we adopted a sphere forma...

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Detalles Bibliográficos
Autores principales: Wang, Hua, Tan, Yinfeng, Jia, Hao, Liu, Danqi, Liu, Rangru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403519/
https://www.ncbi.nlm.nih.gov/pubmed/36034873
http://dx.doi.org/10.3389/fphar.2022.905082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403519/
https://www.ncbi.nlm.nih.gov/pubmed/36034873
http://dx.doi.org/10.3389/fphar.2022.905082

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