Structure based design of effective HtpG-derived vaccine antigens against M. tuberculosis

Vaccine development against Tuberculosis is a strong need, given the low efficacy of the sole vaccine hitherto used, the Bacillus Calmette–Guérin (BCG) vaccine. The chaperone-like protein HtpG(Mtb) of M. tuberculosis is a large dimeric and multi-domain protein with promising antigenic properties. We...

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Detalles Bibliográficos
Autores principales: Ruggiero, Alessia, Choi, Han-Gyu, Barra, Giovanni, Squeglia, Flavia, Back, Young Woo, Kim, Hwa-Jung, Berisio, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403545/
https://www.ncbi.nlm.nih.gov/pubmed/36032688
http://dx.doi.org/10.3389/fmolb.2022.964645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403545/
https://www.ncbi.nlm.nih.gov/pubmed/36032688
http://dx.doi.org/10.3389/fmolb.2022.964645

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