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Structure based design of effective HtpG-derived vaccine antigens against M. tuberculosis
Vaccine development against Tuberculosis is a strong need, given the low efficacy of the sole vaccine hitherto used, the Bacillus Calmette–Guérin (BCG) vaccine. The chaperone-like protein HtpG(Mtb) of M. tuberculosis is a large dimeric and multi-domain protein with promising antigenic properties. We...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403545/ https://www.ncbi.nlm.nih.gov/pubmed/36032688 http://dx.doi.org/10.3389/fmolb.2022.964645 |