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Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review

Foods incorporated with bioactive compounds, called nutraceuticals, can fight or prevent or alleviate diseases. The contribution of nutraceuticals or phytochemicals to non-invasive biomedical applications is increasing. Although there are many traditional methods for extracting bioactive compounds o...

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Autores principales: Mounika, Addanki, Ilangovan, Bhaargavi, Mandal, Sushmita, Shraddha Yashwant, Waghaye, Priya Gali, Swetha, Shanmugam, Akalya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403563/
https://www.ncbi.nlm.nih.gov/pubmed/35987106
http://dx.doi.org/10.1016/j.ultsonch.2022.106121
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author Mounika, Addanki
Ilangovan, Bhaargavi
Mandal, Sushmita
Shraddha Yashwant, Waghaye
Priya Gali, Swetha
Shanmugam, Akalya
author_facet Mounika, Addanki
Ilangovan, Bhaargavi
Mandal, Sushmita
Shraddha Yashwant, Waghaye
Priya Gali, Swetha
Shanmugam, Akalya
author_sort Mounika, Addanki
collection PubMed
description Foods incorporated with bioactive compounds, called nutraceuticals, can fight or prevent or alleviate diseases. The contribution of nutraceuticals or phytochemicals to non-invasive biomedical applications is increasing. Although there are many traditional methods for extracting bioactive compounds or secondary metabolites, these processes come with many disadvantages like lower yield, longer process time, high energy consumption, more usage of solvent, yielding low active principles with low efficacy against diseases, poor quality, poor mass transfer, higher extraction temperature, etc. However, nullifying all these disadvantages of a non-thermal technology, ultrasound has played a significant role in delivering them with higher yield and improved bio-efficacy. The physical and chemical effects of acoustic cavitation are the crux of the output. This review paper primarily discusses the ultrasound-assisted extraction (USAE) of bioactives in providing non-invasive prevention and cure to diseases and bodily dysfunctions in human and animal models. The outputs of non-invasive bioactive components in terms of yield and the clinical efficacy in either in vitro or in vitro conditions are discussed in detail. The non-invasive biomedical applications of USAE bioactives providing anticancer, antioxidant, cardiovascular health, antidiabetic, and antimicrobial benefits are analyzed in-depth and appraised. This review additionally highlights the improved performance of USAE compounds against conventionally extracted compounds. In addition, an exhaustive analysis is performed on the role and application of the food bioactives in vivo and in vitro systems, mainly for promoting these efficient USAE bioactives in non-invasive biomedical applications. Also, the review explores the recovery of bioactives from the less explored food sources like cactus pear fruit, ash gourd, sweet granadilla, basil, kokum, baobab, and the food processing industrial wastes like peel, pomace, propolis, wine residues, bran, etc., which is rare in literature.
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spelling pubmed-94035632022-08-26 Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review Mounika, Addanki Ilangovan, Bhaargavi Mandal, Sushmita Shraddha Yashwant, Waghaye Priya Gali, Swetha Shanmugam, Akalya Ultrason Sonochem Review Article Foods incorporated with bioactive compounds, called nutraceuticals, can fight or prevent or alleviate diseases. The contribution of nutraceuticals or phytochemicals to non-invasive biomedical applications is increasing. Although there are many traditional methods for extracting bioactive compounds or secondary metabolites, these processes come with many disadvantages like lower yield, longer process time, high energy consumption, more usage of solvent, yielding low active principles with low efficacy against diseases, poor quality, poor mass transfer, higher extraction temperature, etc. However, nullifying all these disadvantages of a non-thermal technology, ultrasound has played a significant role in delivering them with higher yield and improved bio-efficacy. The physical and chemical effects of acoustic cavitation are the crux of the output. This review paper primarily discusses the ultrasound-assisted extraction (USAE) of bioactives in providing non-invasive prevention and cure to diseases and bodily dysfunctions in human and animal models. The outputs of non-invasive bioactive components in terms of yield and the clinical efficacy in either in vitro or in vitro conditions are discussed in detail. The non-invasive biomedical applications of USAE bioactives providing anticancer, antioxidant, cardiovascular health, antidiabetic, and antimicrobial benefits are analyzed in-depth and appraised. This review additionally highlights the improved performance of USAE compounds against conventionally extracted compounds. In addition, an exhaustive analysis is performed on the role and application of the food bioactives in vivo and in vitro systems, mainly for promoting these efficient USAE bioactives in non-invasive biomedical applications. Also, the review explores the recovery of bioactives from the less explored food sources like cactus pear fruit, ash gourd, sweet granadilla, basil, kokum, baobab, and the food processing industrial wastes like peel, pomace, propolis, wine residues, bran, etc., which is rare in literature. Elsevier 2022-08-12 /pmc/articles/PMC9403563/ /pubmed/35987106 http://dx.doi.org/10.1016/j.ultsonch.2022.106121 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Mounika, Addanki
Ilangovan, Bhaargavi
Mandal, Sushmita
Shraddha Yashwant, Waghaye
Priya Gali, Swetha
Shanmugam, Akalya
Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review
title Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review
title_full Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review
title_fullStr Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review
title_full_unstemmed Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review
title_short Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review
title_sort prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – a review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403563/
https://www.ncbi.nlm.nih.gov/pubmed/35987106
http://dx.doi.org/10.1016/j.ultsonch.2022.106121
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