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Efficient screening of pancreatic lipase inhibitors from cod meat hydrolysate through ligand fishing strategy

Obesity has become an increasingly serious public health problem. Pancreatic lipase (PL) is identified as a ideal target for the prevention and treatment of obesity. Orlistat, the only approved PL inhibitor (PLI), is a powerful weight loss drug but has many side effects. Therefore, there is an urgen...

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Detalles Bibliográficos
Autores principales: Tian, Yongqi, Liu, Cuicui, Wang, Shaoyun, Du, Ming, Zhu, Beiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403610/
https://www.ncbi.nlm.nih.gov/pubmed/36034931
http://dx.doi.org/10.3389/fnut.2022.969558