A novel procedure for the synthesis of borylated quinolines and its application in the development of potential boron-based homeodomain interacting protein kinase 2 (HIPK2) inhibitors

Herein, we demonstrate a Pd catalyzed C-4 borylation of structurally complex chloroquinolines with bis(pinacolato)diboron under relatively simple and efficient conditions. Moreover, the borylated quinolines were converted into oxaborole, trifluoroborate salt and boronic acid and also rendered in the...

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Detalles Bibliográficos
Autores principales: Das, Bhaskar C., Yadav, Pratik, Das, Sasmita, He, John Cijiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403659/
https://www.ncbi.nlm.nih.gov/pubmed/36128533
http://dx.doi.org/10.1039/d2ra05063c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403659/
https://www.ncbi.nlm.nih.gov/pubmed/36128533
http://dx.doi.org/10.1039/d2ra05063c

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