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Protein Kinase CK2 represents a new target to boost Ibrutinib and Venetoclax induced cytotoxicity in mantle cell lymphoma

Mantle cell lymphoma (MCL) is an incurable B cell non-Hodgkin lymphoma, characterized by frequent relapses. In the last decade, the pro-survival pathways related to BCR signaling and Bcl-2 have been considered rational therapeutic targets in B cell derived lymphomas. The BTK inhibitor Ibrutinib and...

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Detalles Bibliográficos
Autores principales: Manni, Sabrina, Pesavento, Maria, Spinello, Zaira, Saggin, Lara, Arjomand, Arash, Fregnani, Anna, Quotti Tubi, Laura, Scapinello, Greta, Gurrieri, Carmela, Semenzato, Gianpietro, Trentin, Livio, Piazza, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403710/
https://www.ncbi.nlm.nih.gov/pubmed/36035991
http://dx.doi.org/10.3389/fcell.2022.935023