Development and characterization of a CRISPR/Cas9-mediated RAG1 knockout chicken model lacking mature B and T cells

Although birds have been used historically as a model animal for immunological research, resulting in remarkable achievements, immune cell development in birds themselves has yet to be fully elucidated. In this study, we firstly generated an immunodeficient chicken model using a CRISPR/Cas9-mediated...

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Detalles Bibliográficos
Autores principales: Lee, Kyung Youn, Choi, Hyeon Jeong, Park, Kyung Je, Woo, Seung Je, Kim, Young Min, Han, Jae Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403712/
https://www.ncbi.nlm.nih.gov/pubmed/36032098
http://dx.doi.org/10.3389/fimmu.2022.892476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403712/
https://www.ncbi.nlm.nih.gov/pubmed/36032098
http://dx.doi.org/10.3389/fimmu.2022.892476

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