Rationale and design of the prevention of paclitaxel-related neurological side effects with lithium trial – Protocol of a multicenter, randomized, double-blind, placebo- controlled proof-of-concept phase-2 clinical trial

INTRODUCTION: Chemotherapy-induced polyneuropathy (CIPN) and post-chemotherapy cognitive impairment (PCCI) are frequent side effects of paclitaxel treatment. CIPN/PCCI are potentially irreversible, reduce quality of life and often lead to treatment limitations, which affect patients’ outcome. We pre...

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Detalles Bibliográficos
Autores principales: Huehnchen, Petra, Bangemann, Nikola, Lischewski, Sandra, Märschenz, Stefanie, Paul, Friedemann, Schmitz-Hübsch, Tanja, Blohmer, Jens-Uwe, Eberhardt, Cornelia, Rauch, Geraldine, Flöel, Agnes, Adam, Sophie, Schwenkenbecher, Philipp, Meinhold-Heerlein, Ivo, Hoffmann, Oliver, Ziemssen, Tjalf, Endres, Matthias, Boehmerle, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403739/
https://www.ncbi.nlm.nih.gov/pubmed/36035422
http://dx.doi.org/10.3389/fmed.2022.967964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403739/
https://www.ncbi.nlm.nih.gov/pubmed/36035422
http://dx.doi.org/10.3389/fmed.2022.967964

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