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FGF8–FGFR1 signaling regulates human GnRH neuron differentiation in a time- and dose-dependent manner

Fibroblast growth factor 8 (FGF8), acting through the fibroblast growth factor receptor 1 (FGFR1), has an important role in the development of gonadotropin-releasing hormone-expressing neurons (GnRH neurons). We hypothesized that FGF8 regulates differentiation of human GnRH neurons in a time- and do...

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Detalles Bibliográficos
Autores principales: Yellapragada, Venkatram, Eskici, Nazli, Wang, Yafei, Madhusudan, Shrinidhi, Vaaralahti, Kirsi, Tuuri, Timo, Raivio, Taneli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403748/
https://www.ncbi.nlm.nih.gov/pubmed/35833364
http://dx.doi.org/10.1242/dmm.049436