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Pharmacological intervention of the FGF–PTH axis as a potential therapeutic for craniofacial ciliopathies

Ciliopathies represent a disease class characterized by a broad range of phenotypes including polycystic kidneys and skeletal anomalies. Ciliopathic skeletal phenotypes are among the most common and most difficult to treat due to a poor understanding of the pathological mechanisms leading to disease...

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Detalles Bibliográficos
Autores principales: Bonatto Paese, Christian Louis, Chang, Ching-Fang, Kristeková, Daniela, Brugmann, Samantha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403750/
https://www.ncbi.nlm.nih.gov/pubmed/35818799
http://dx.doi.org/10.1242/dmm.049611