Mercury Ion Binding to Apolipoprotein E Variants ApoE2, ApoE3, and ApoE4: Similar Binding Affinities but Different Structure Induction Effects

[Image: see text] Mercury intoxication typically produces more severe outcomes in people with the APOE-ε4 gene, which codes for the ApoE4 variant of apolipoprotein E, compared to individuals with the APOE-ε2 and APOE-ε3 genes. Why the APOE-ε4 allele is a risk factor in mercury exposure remains unkno...

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Detalles Bibliográficos
Autores principales: Berntsson, Elina, Sardis, Merlin, Noormägi, Andra, Jarvet, Jüri, Roos, Per M., Tõugu, Vello, Gräslund, Astrid, Palumaa, Peep, Wärmländer, Sebastian K. T. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404194/
https://www.ncbi.nlm.nih.gov/pubmed/36033665
http://dx.doi.org/10.1021/acsomega.2c02254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404194/
https://www.ncbi.nlm.nih.gov/pubmed/36033665
http://dx.doi.org/10.1021/acsomega.2c02254

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