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伊曲茶碱中间体杂质的分离与鉴定

Istradefylline is a novel selective adenosine A(2A) receptor antagonist that is used to treat Parkinson’s disease and improve motor dysfunction in the early stage of this disease. During the synthesis of intermediate A1 (6-amino-1,3-diethyl-2,4-(1H,3H)-pyrimidinedione), at least two by-products were...

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Detalles Bibliográficos
Autores principales: WANG, Yiyun, LÜ, Xiaofang, XU, Haojie, MENG, Zihu, LI, Jiarong, XU, Zhibin, XUE, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial board of Chinese Journal of Chromatography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404203/
https://www.ncbi.nlm.nih.gov/pubmed/34227764
http://dx.doi.org/10.3724/SP.J.1123.2020.10013