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ACPA-negative rheumatoid arthritis: From immune mechanisms to clinical translation
The presence of anti-citrullinated protein autoantibodies (ACPA) is a hallmark feature of rheumatoid arthritis (RA), which causes chronic joint destruction and systemic inflammation. Based on ACPA status, RA patients can be sub-grouped into two major subsets: ACPA-positive RA (ACPA(+) RA) and ACPA-n...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404277/ https://www.ncbi.nlm.nih.gov/pubmed/36027873 http://dx.doi.org/10.1016/j.ebiom.2022.104233 |