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Design and experimental validation of OPERA_MET-A panel for deep methylation analysis by next generation sequencing

DNA methylation is the most recognized epigenetic mark that leads to a massive distortion in cancer cells. It has been observed that a large number of DNA aberrant methylation events occur simultaneously in a group of genes, thus providing a growth advantage to the cell in promoting cell differentia...

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Detalles Bibliográficos
Autores principales: Fabrizio, Federico Pio, Castellana, Stefano, Centra, Flavia, Sparaneo, Angelo, Mastroianno, Mario, Mazza, Tommaso, Coco, Michelina, Trombetta, Domenico, Cingolani, Nicola, Centonza, Antonella, Graziano, Paolo, Maiello, Evaristo, Fazio, Vito Michele, Muscarella, Lucia Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404304/
https://www.ncbi.nlm.nih.gov/pubmed/36033501
http://dx.doi.org/10.3389/fonc.2022.968804