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Design and experimental validation of OPERA_MET-A panel for deep methylation analysis by next generation sequencing
DNA methylation is the most recognized epigenetic mark that leads to a massive distortion in cancer cells. It has been observed that a large number of DNA aberrant methylation events occur simultaneously in a group of genes, thus providing a growth advantage to the cell in promoting cell differentia...
Autores principales: | Fabrizio, Federico Pio, Castellana, Stefano, Centra, Flavia, Sparaneo, Angelo, Mastroianno, Mario, Mazza, Tommaso, Coco, Michelina, Trombetta, Domenico, Cingolani, Nicola, Centonza, Antonella, Graziano, Paolo, Maiello, Evaristo, Fazio, Vito Michele, Muscarella, Lucia Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404304/ https://www.ncbi.nlm.nih.gov/pubmed/36033501 http://dx.doi.org/10.3389/fonc.2022.968804 |
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