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Potential molecular mechanism in self-renewal is associated with miRNA dysregulation in sacral chordoma – A next-generation RNA sequencing study

BACKGROUND: Chordoma, the most frequent malignant primary spinal neoplasm, characterized by a high rate of recurrence, is an orphan disease where the clarification of the molecular oncogenesis would be crucial to developing new, effective therapies. Dysregulated expression of non-coding RNAs, especi...

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Detalles Bibliográficos
Autores principales: Bozsodi, Arpad, Scholtz, Beata, Papp, Gergo, Sapi, Zoltan, Biczo, Adam, Varga, Peter Pal, Lazary, Aron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404356/
https://www.ncbi.nlm.nih.gov/pubmed/36033338
http://dx.doi.org/10.1016/j.heliyon.2022.e10227