Inhibitory Effects of 3′,4′-Dihydroxyflavonol in a Mouse Model of Glaucoma Filtration Surgery and TGFβ1-Induced Responses in Human Tenon's Fibroblasts

PURPOSE: Cytotoxic agents such as mitomycin C (MMC) are part of the mainstay treatment for limiting subconjunctival scarring following glaucoma filtration surgery (GFS). However, a safer antifibrotic therapy is clinically needed. The anti-scarring properties of 3′,4′-dihydroxyflavonol (DiOHF) were e...

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Detalles Bibliográficos
Autores principales: Fan Gaskin, Jennifer C., Kong, Roy C. K., Shah, Manisha H., Edgley, Amanda J., Peshavariya, Hitesh M., Chan, Elsa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404366/
https://www.ncbi.nlm.nih.gov/pubmed/35980669
http://dx.doi.org/10.1167/tvst.11.8.18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404366/
https://www.ncbi.nlm.nih.gov/pubmed/35980669
http://dx.doi.org/10.1167/tvst.11.8.18

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