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Inhibitory Effects of 3′,4′-Dihydroxyflavonol in a Mouse Model of Glaucoma Filtration Surgery and TGFβ1-Induced Responses in Human Tenon's Fibroblasts
PURPOSE: Cytotoxic agents such as mitomycin C (MMC) are part of the mainstay treatment for limiting subconjunctival scarring following glaucoma filtration surgery (GFS). However, a safer antifibrotic therapy is clinically needed. The anti-scarring properties of 3′,4′-dihydroxyflavonol (DiOHF) were e...
Autores principales: | Fan Gaskin, Jennifer C., Kong, Roy C. K., Shah, Manisha H., Edgley, Amanda J., Peshavariya, Hitesh M., Chan, Elsa C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404366/ https://www.ncbi.nlm.nih.gov/pubmed/35980669 http://dx.doi.org/10.1167/tvst.11.8.18 |
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