Evaluation of the Dose-Dependent Inflammatory Response and No-Observable Adverse Effect Level of Intravitreal Endotoxin in the African Green Monkey

PURPOSE: To evaluate the inflammatory effects and no-observed adverse effect level (NOAEL) of intravitreal endotoxin in an African green monkey model of uveitis. METHODS: Fifteen green monkeys were administered intravitreal endotoxin ranging from 0.005 to 0.08 endotoxin unit (EU)/eye. Inflammation w...

Descripción completa

Detalles Bibliográficos
Autores principales: Corey, Tatiana M., Woodley, Vernard V., O'Connor, Merissa, Connolly, Emma, Doyle, Sarah, Shrader, Stephanie, Phipps, Cyrene, Isaac, Kimicia, Lawrence, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Uveitis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404367/
https://www.ncbi.nlm.nih.gov/pubmed/35980670
http://dx.doi.org/10.1167/tvst.11.8.17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404367/
https://www.ncbi.nlm.nih.gov/pubmed/35980670
http://dx.doi.org/10.1167/tvst.11.8.17

Ejemplares similares