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Evaluation of the Dose-Dependent Inflammatory Response and No-Observable Adverse Effect Level of Intravitreal Endotoxin in the African Green Monkey

PURPOSE: To evaluate the inflammatory effects and no-observed adverse effect level (NOAEL) of intravitreal endotoxin in an African green monkey model of uveitis. METHODS: Fifteen green monkeys were administered intravitreal endotoxin ranging from 0.005 to 0.08 endotoxin unit (EU)/eye. Inflammation w...

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Detalles Bibliográficos
Autores principales:	Corey, Tatiana M., Woodley, Vernard V., O'Connor, Merissa, Connolly, Emma, Doyle, Sarah, Shrader, Stephanie, Phipps, Cyrene, Isaac, Kimicia, Lawrence, Matthew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2022
Materias:	Uveitis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404367/ https://www.ncbi.nlm.nih.gov/pubmed/35980670 http://dx.doi.org/10.1167/tvst.11.8.17

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