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SHH and Notch regulate SOX9+ progenitors to govern arcuate POMC neurogenesis

Pro-opiomelanocortin (POMC)-expressing neurons in the hypothalamic arcuate nucleus (ARC) play key roles in feeding and energy homoeostasis, hence their development is of great research interest. As the process of neurogenesis is accompanied by changes in adhesion, polarity, and migration that resemb...

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Detalles Bibliográficos
Autores principales: Place, Elsie, Manning, Elizabeth, Kim, Dong Won, Kinjo, Arisa, Nakamura, Go, Ohyama, Kyoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404380/
https://www.ncbi.nlm.nih.gov/pubmed/36033614
http://dx.doi.org/10.3389/fnins.2022.855288