Red Blood Cell Anchoring Enables Targeted Transduction and Re‐Administration of AAV‐Mediated Gene Therapy

Adeno‐associated virus (AAV)‐mediated gene therapy is a promising therapeutic modality for curing many diseases including monogenic diseases. However, limited tissue‐targeting and restricted re‐administration due to the vector immunogenicity largely restrict its therapeutic potential. Here, using a...

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Detalles Bibliográficos
Autores principales: Zhao, Zongmin, Kim, Jayoung, Suja, Vinny Chandran, Kapate, Neha, Gao, Yongsheng, Guo, Junling, Muzykantov, Vladimir R., Mitragotri, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404386/
https://www.ncbi.nlm.nih.gov/pubmed/35780495
http://dx.doi.org/10.1002/advs.202201293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404386/
https://www.ncbi.nlm.nih.gov/pubmed/35780495
http://dx.doi.org/10.1002/advs.202201293

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