Mesenchymal Stromal Cells Overexpressing Farnesoid X Receptor Exert Cardioprotective Effects Against Acute Ischemic Heart Injury by Binding Endogenous Bile Acids

Bile acid metabolites have been increasingly recognized as pleiotropic signaling molecules that regulate cardiovascular functions, but their role in mesenchymal stromal cells (MSC)‐based therapy has never been investigated. It is found that overexpression of farnesoid X receptor (FXR), a main recept...

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Detalles Bibliográficos
Autores principales: Xia, Yunlong, Xu, Xinyue, Guo, Yongzhen, Lin, Chen, Xu, Xiaoming, Zhang, Fuyang, Fan, Miaomiao, Qi, Tingting, Li, Congye, Hu, Guangyu, Peng, Lu, Wang, Shan, Zhang, Ling, Hai, Chunxu, Liu, Rui, Yan, Wenjun, Tao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404394/
https://www.ncbi.nlm.nih.gov/pubmed/35780502
http://dx.doi.org/10.1002/advs.202200431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404394/
https://www.ncbi.nlm.nih.gov/pubmed/35780502
http://dx.doi.org/10.1002/advs.202200431

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