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Mesenchymal Stromal Cells Overexpressing Farnesoid X Receptor Exert Cardioprotective Effects Against Acute Ischemic Heart Injury by Binding Endogenous Bile Acids
Bile acid metabolites have been increasingly recognized as pleiotropic signaling molecules that regulate cardiovascular functions, but their role in mesenchymal stromal cells (MSC)‐based therapy has never been investigated. It is found that overexpression of farnesoid X receptor (FXR), a main recept...
Autores principales: | Xia, Yunlong, Xu, Xinyue, Guo, Yongzhen, Lin, Chen, Xu, Xiaoming, Zhang, Fuyang, Fan, Miaomiao, Qi, Tingting, Li, Congye, Hu, Guangyu, Peng, Lu, Wang, Shan, Zhang, Ling, Hai, Chunxu, Liu, Rui, Yan, Wenjun, Tao, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404394/ https://www.ncbi.nlm.nih.gov/pubmed/35780502 http://dx.doi.org/10.1002/advs.202200431 |
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