Tumor‐Activatable Nanoparticles Target Low‐Density Lipoprotein Receptor to Enhance Drug Delivery and Antitumor Efficacy

The binding of plasma proteins to nanomedicines is widely considered detrimental to their delivery to tumors. Here, the design of OxPt/SN38 nanoparticle containing a hydrophilic oxaliplatin (OxPt) prodrug in a coordination polymer core and a hydrophobic cholesterol‐conjugated SN38 prodrug on the lip...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Xiaomin, Han, Wenbo, Liu, Jianqiao, Mao, Jianming, Lee, Morten J., Rodriguez, Megan, Li, Youyou, Luo, Taokun, Xu, Ziwan, Yang, Kaiting, Bissonnette, Marc, Weichselbaum, Ralph R., Lin, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404402/
https://www.ncbi.nlm.nih.gov/pubmed/35748191
http://dx.doi.org/10.1002/advs.202201614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404402/
https://www.ncbi.nlm.nih.gov/pubmed/35748191
http://dx.doi.org/10.1002/advs.202201614

Ejemplares similares