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Metabolic Signatures of Surface-Modified Poly(lactic-co-glycolic acid) Nanoparticles in Differentiated THP-1 Cells Derived with Liquid Chromatography-Mass Spectrometry-based Metabolomics

[Image: see text] Polymeric nanoparticles (NPs) are widely used in preclinical drug delivery investigations, and some formulations are now in the clinic. However, the detailed effects of many NPs at the subcellular level have not been fully investigated. In this study, we used differentiated THP-1 m...

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Detalles Bibliográficos
Autores principales: Al-natour, Mohammad A., Abdelrazig, Salah, Ghaemmaghami, Amir M., Alexander, Cameron, Kim, Dong-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404530/
https://www.ncbi.nlm.nih.gov/pubmed/36033713
http://dx.doi.org/10.1021/acsomega.2c01660