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Metabolic Signatures of Surface-Modified Poly(lactic-co-glycolic acid) Nanoparticles in Differentiated THP-1 Cells Derived with Liquid Chromatography-Mass Spectrometry-based Metabolomics
[Image: see text] Polymeric nanoparticles (NPs) are widely used in preclinical drug delivery investigations, and some formulations are now in the clinic. However, the detailed effects of many NPs at the subcellular level have not been fully investigated. In this study, we used differentiated THP-1 m...
Autores principales: | Al-natour, Mohammad A., Abdelrazig, Salah, Ghaemmaghami, Amir M., Alexander, Cameron, Kim, Dong-Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404530/ https://www.ncbi.nlm.nih.gov/pubmed/36033713 http://dx.doi.org/10.1021/acsomega.2c01660 |
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