Orally administered Odoribacter laneus improves glucose control and inflammatory profile in obese mice by depleting circulating succinate

BACKGROUND: Succinate is produced by both human cells and by gut bacteria and couples metabolism to inflammation as an extracellular signaling transducer. Circulating succinate is elevated in patients with obesity and type 2 diabetes and is linked to numerous complications, yet no studies have speci...

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Detalles Bibliográficos
Autores principales: Huber-Ruano, Isabel, Calvo, Enrique, Mayneris-Perxachs, Jordi, Rodríguez-Peña, M-Mar, Ceperuelo-Mallafré, Victòria, Cedó, Lídia, Núñez-Roa, Catalina, Miro-Blanch, Joan, Arnoriaga-Rodríguez, María, Balvay, Aurélie, Maudet, Claire, García-Roves, Pablo, Yanes, Oscar, Rabot, Sylvie, Grimaud, Ghjuvan Micaelu, De Prisco, Annachiara, Amoruso, Angela, Fernández-Real, José Manuel, Vendrell, Joan, Fernández-Veledo, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404562/
https://www.ncbi.nlm.nih.gov/pubmed/36002880
http://dx.doi.org/10.1186/s40168-022-01306-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404562/
https://www.ncbi.nlm.nih.gov/pubmed/36002880
http://dx.doi.org/10.1186/s40168-022-01306-y

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