Cargando…
Orally administered Odoribacter laneus improves glucose control and inflammatory profile in obese mice by depleting circulating succinate
BACKGROUND: Succinate is produced by both human cells and by gut bacteria and couples metabolism to inflammation as an extracellular signaling transducer. Circulating succinate is elevated in patients with obesity and type 2 diabetes and is linked to numerous complications, yet no studies have speci...
Autores principales: | Huber-Ruano, Isabel, Calvo, Enrique, Mayneris-Perxachs, Jordi, Rodríguez-Peña, M-Mar, Ceperuelo-Mallafré, Victòria, Cedó, Lídia, Núñez-Roa, Catalina, Miro-Blanch, Joan, Arnoriaga-Rodríguez, María, Balvay, Aurélie, Maudet, Claire, García-Roves, Pablo, Yanes, Oscar, Rabot, Sylvie, Grimaud, Ghjuvan Micaelu, De Prisco, Annachiara, Amoruso, Angela, Fernández-Real, José Manuel, Vendrell, Joan, Fernández-Veledo, Sonia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404562/ https://www.ncbi.nlm.nih.gov/pubmed/36002880 http://dx.doi.org/10.1186/s40168-022-01306-y |
Ejemplares similares
-
Impaired Succinate Response to a Mixed Meal in Obesity and Type 2 Diabetes Is Normalized After Metabolic Surgery
por: Astiarraga, Brenno, et al.
Publicado: (2020) -
Adipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans
por: Ceperuelo-Mallafré, Victòria, et al.
Publicado: (2015) -
Zinc-α2-Glycoprotein Modulates AKT-Dependent Insulin Signaling in Human Adipocytes by Activation of the PP2A Phosphatase
por: Ceperuelo-Mallafré, Victòria, et al.
Publicado: (2015) -
Protocol for the in vitro isolation and culture of mature adipocytes and white adipose tissue explants from humans and mice
por: Villanueva-Carmona, Teresa, et al.
Publicado: (2023) -
Effects of stem cells from inducible brown adipose tissue on diet-induced obesity in mice
por: Calvo, Enrique, et al.
Publicado: (2021)