Co-deposition of SOD1, TDP-43 and p62 proteinopathies in ALS: evidence for multifaceted pathways underlying neurodegeneration

Multiple neurotoxic proteinopathies co-exist within vulnerable neuronal populations in all major neurodegenerative diseases. Interactions between these pathologies may modulate disease progression, suggesting they may constitute targets for disease-modifying treatments aiming to slow or halt neurode...

Descripción completa

Detalles Bibliográficos
Autores principales: Trist, Benjamin G., Fifita, Jennifer A., Hogan, Alison, Grima, Natalie, Smith, Bradley, Troakes, Claire, Vance, Caroline, Shaw, Christopher, Al-Sarraj, Safa, Blair, Ian P., Double, Kay L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404564/
https://www.ncbi.nlm.nih.gov/pubmed/36008843
http://dx.doi.org/10.1186/s40478-022-01421-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404564/
https://www.ncbi.nlm.nih.gov/pubmed/36008843
http://dx.doi.org/10.1186/s40478-022-01421-9

Ejemplares similares