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Co-deposition of SOD1, TDP-43 and p62 proteinopathies in ALS: evidence for multifaceted pathways underlying neurodegeneration
Multiple neurotoxic proteinopathies co-exist within vulnerable neuronal populations in all major neurodegenerative diseases. Interactions between these pathologies may modulate disease progression, suggesting they may constitute targets for disease-modifying treatments aiming to slow or halt neurode...
Autores principales: | Trist, Benjamin G., Fifita, Jennifer A., Hogan, Alison, Grima, Natalie, Smith, Bradley, Troakes, Claire, Vance, Caroline, Shaw, Christopher, Al-Sarraj, Safa, Blair, Ian P., Double, Kay L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404564/ https://www.ncbi.nlm.nih.gov/pubmed/36008843 http://dx.doi.org/10.1186/s40478-022-01421-9 |
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