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Single cell RNA-seq analysis reveals temporally-regulated and quiescence-regulated gene expression in Drosophila larval neuroblasts

The mechanisms that generate neural diversity during development remains largely unknown. Here, we use scRNA-seq methodology to discover new features of the Drosophila larval CNS across several key developmental timepoints. We identify multiple progenitor subtypes – both stem cell-like neuroblasts a...

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Detalles Bibliográficos
Autores principales: Dillon, Noah, Cocanougher, Ben, Sood, Chhavi, Yuan, Xin, Kohn, Andrea B, Moroz, Leonid L, Siegrist, Sarah E, Zlatic, Marta, Doe, Chris Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404614/
https://www.ncbi.nlm.nih.gov/pubmed/36002894
http://dx.doi.org/10.1186/s13064-022-00163-7