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C-Locked Analogs of the Antimicrobial Peptide BP214

BP214 is an all-D antimicrobial peptide amide, kklfkkilryl, which shows an excellent activity against colistin-resistant Acinetobacter baumannii and a low hemolytic activity. The aim of the present work was to investigate how C-terminus-to-side chain macrocyclization and fatty acid modification affe...

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Detalles Bibliográficos
Autores principales: Andersen, Ida Kristine Lysgaard, Thomsen, Thomas T., Rashid, Jasmina, Bobak, Thomas Rønnemoes, Oddo, Alberto, Franzyk, Henrik, Løbner-Olesen, Anders, Hansen, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404711/
https://www.ncbi.nlm.nih.gov/pubmed/36009951
http://dx.doi.org/10.3390/antibiotics11081080