Reverse and Forward Electron Flow-Induced H(2)O(2) Formation Is Decreased in α-Ketoglutarate Dehydrogenase (α-KGDH) Subunit (E2 or E3) Heterozygote Knock Out Animals

α-ketoglutarate dehydrogenase complex (KGDHc), or 2-oxoglutarate dehydrogenase complex (OGDHc) is a rate-limiting enzyme in the tricarboxylic acid cycle, that has been identified in neurodegenerative diseases such as in Alzheimer’s disease. The aim of the present study was to establish the role of t...

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Detalles Bibliográficos
Autores principales: Horváth, Gergő, Sváb, Gergely, Komlódi, Tímea, Ravasz, Dora, Kacsó, Gergely, Doczi, Judit, Chinopoulos, Christos, Ambrus, Attila, Tretter, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404749/
https://www.ncbi.nlm.nih.gov/pubmed/36009207
http://dx.doi.org/10.3390/antiox11081487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404749/
https://www.ncbi.nlm.nih.gov/pubmed/36009207
http://dx.doi.org/10.3390/antiox11081487

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