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A Novel Automatic Quantification Protocol for Biomarkers of Tauopathies in the Hippocampus and Entorhinal Cortex of Post-Mortem Samples Using an Extended Semi-Siamese U-Net

SIMPLE SUMMARY: Tauopathies is a term coined to describe an umbrella of disorders characterized by abnormal Tau polypeptide deposits in neurons, glial cells, and extracellular space. In this work, we propose a novel quantification protocol for the study of tauopathies based on the U-Net neural netwo...

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Detalles Bibliográficos
Autores principales: Campero-Garcia, Luis A., Cantoral-Ceballos, Jose A., Martinez-Maldonado, Alejandra, Luna-Muñoz, Jose, Ontiveros-Torres, Miguel A., Gutierrez-Rodriguez, Andres E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404816/
https://www.ncbi.nlm.nih.gov/pubmed/36009757
http://dx.doi.org/10.3390/biology11081131