The Structures and Binding Modes of Small-Molecule Inhibitors of Pseudomonas aeruginosa Elastase LasB

Elastase B (LasB) is a zinc metalloprotease and a crucial virulence factor of Pseudomonas aeruginosa. As the need for new strategies to fight antimicrobial resistance (AMR) constantly rises, this protein has become a key target in the development of novel antivirulence agents. The extensive knowledg...

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Detalles Bibliográficos
Autores principales: Camberlein, Virgyl, Jézéquel, Gwenaëlle, Haupenthal, Jörg, Hirsch, Anna K. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404851/
https://www.ncbi.nlm.nih.gov/pubmed/36009930
http://dx.doi.org/10.3390/antibiotics11081060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404851/
https://www.ncbi.nlm.nih.gov/pubmed/36009930
http://dx.doi.org/10.3390/antibiotics11081060

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