Mitochondria Targeted Antioxidant Significantly Alleviates Preeclampsia Caused by 11β-HSD2 Dysfunction via OPA1 and MtDNA Maintenance

We have previously demonstrated that placental 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) dysfunction contributes to PE pathogenesis. We sought to elucidate molecular mechanisms underlying 11β-HSD2 dysfunction-induced PE and to seek potential therapeutic targets using a 11β-HSD2 dysfunction-...

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Detalles Bibliográficos
Autores principales: Long, Jing, Huang, Yan, Tang, Zhengshan, Shan, Yali, Feng, Dou, Wang, Wenqin, Liu, Juan, Huang, Ying, Gu, Hang, Guo, Dewei, Yao, Ruojin, Ni, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404992/
https://www.ncbi.nlm.nih.gov/pubmed/36009224
http://dx.doi.org/10.3390/antiox11081505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404992/
https://www.ncbi.nlm.nih.gov/pubmed/36009224
http://dx.doi.org/10.3390/antiox11081505

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