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NRF2 Regulates Cystathionine Gamma-Lyase Expression and Activity in Primary Airway Epithelial Cells Infected with Respiratory Syncytial Virus

Cystathionine-y-lyase (CSE) is a critical enzyme for hydrogen sulfide (H(2)S) biosynthesis and plays a key role in respiratory syncytial virus (RSV) pathogenesis. The transcription factor NRF2 is the master regulator of cytoprotective and antioxidant gene expression, and is degraded during RSV infec...

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Detalles Bibliográficos
Autores principales: Jamaluddin, Mohammad, Haas de Mello, Aline, Tapryal, Nisha, Hazra, Tapas K., Garofalo, Roberto P., Casola, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405023/
https://www.ncbi.nlm.nih.gov/pubmed/36009301
http://dx.doi.org/10.3390/antiox11081582