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NRSF/REST-Mediated Epigenomic Regulation in the Heart: Transcriptional Control of Natriuretic Peptides and Beyond

SIMPLE SUMMARY: Reactivation of the fetal cardiac gene program, such as those encoding atrial and brain natriuretic peptides (ANP and BNP, respectively), is a characteristic feature of failing hearts. We previously revealed that a transcriptional repressor, neuron-restrictive silencer factor (NRSF),...

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Detalles Bibliográficos
Autores principales: Inazumi, Hideaki, Kuwahara, Koichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405064/
https://www.ncbi.nlm.nih.gov/pubmed/36009824
http://dx.doi.org/10.3390/biology11081197