2-Methoxyestradiol TPGS Micelles Attenuate Cyclosporine A-Induced Nephrotoxicity in Rats through Inhibition of TGF-β1 and p-ERK1/2 Axis

The immunosuppressant cyclosporine A (CSA) has been linked to serious renal toxic effects. Although 2-methoxyestradiol (2ME) possesses a wide range of pharmacological abilities, it suffers poor bioavailability after oral administration. The purpose of this study was to evaluate the potential of 2ME...

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Detalles Bibliográficos
Autores principales: Al-Rabia, Mohammed W., Alfaleh, Mohamed A., Asfour, Hani Z., Alharbi, Waleed S., El-Moselhy, Mohamed A., Alhakamy, Nabil A., Fahmy, Usama A., Ahmed, Osama A. A., Fahmy, Omar, Rashad, Omar M., Alamoudi, Abdulmohsin J., Abdel-Naim, Ashraf B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405159/
https://www.ncbi.nlm.nih.gov/pubmed/36009218
http://dx.doi.org/10.3390/antiox11081499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405159/
https://www.ncbi.nlm.nih.gov/pubmed/36009218
http://dx.doi.org/10.3390/antiox11081499

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