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Integrated molecular and pharmacological characterization of patient-derived xenografts from bladder and ureteral cancers identifies new potential therapies

BACKGROUND: Muscle-invasive bladder cancer (MIBC) and upper urinary tract urothelial carcinoma (UTUC) are molecularly heterogeneous. Despite chemotherapies, immunotherapies, or anti-fibroblast growth factor receptor (FGFR) treatments, these tumors are still of a poor outcome. Our objective was to de...

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Detalles Bibliográficos
Autores principales: Lang, Hervé, Béraud, Claire, Cabel, Luc, Fontugne, Jacqueline, Lassalle, Myriam, Krucker, Clémentine, Dufour, Florent, Groeneveld, Clarice S., Dixon, Victoria, Meng, Xiangyu, Kamoun, Aurélie, Chapeaublanc, Elodie, De Reynies, Aurélien, Gamé, Xavier, Rischmann, Pascal, Bieche, Ivan, Masliah-Planchon, Julien, Beaurepere, Romane, Allory, Yves, Lindner, Véronique, Misseri, Yolande, Radvanyi, François, Lluel, Philippe, Bernard-Pierrot, Isabelle, Massfelder, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405192/
https://www.ncbi.nlm.nih.gov/pubmed/36033544
http://dx.doi.org/10.3389/fonc.2022.930731