Experimentally Deduced Criteria for Detection of Clinically Relevant Fusion 3′ Oncogenes from FFPE Bulk RNA Sequencing Data

Drugs targeting receptor tyrosine kinase (RTK) oncogenic fusion proteins demonstrate impressive anti-cancer activities. The fusion presence in the cancer is the respective drug prescription biomarker, but their identification is challenging as both the breakpoint and the exact fusion partners are un...

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Detalles Bibliográficos
Autores principales: Rabushko, Elizaveta, Sorokin, Maxim, Suntsova, Maria, Seryakov, Alexander P., Kuzmin, Denis V., Poddubskaya, Elena, Buzdin, Anton A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405289/
https://www.ncbi.nlm.nih.gov/pubmed/36009413
http://dx.doi.org/10.3390/biomedicines10081866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405289/
https://www.ncbi.nlm.nih.gov/pubmed/36009413
http://dx.doi.org/10.3390/biomedicines10081866

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